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PHARMACIST’S LETTER and PRESCRIBER’S LETTER March 2003 ~ Volume 19 ~ Number 190314 Excerpt from Detail-Document #190314 - Avlimil for Female Sexual Dysfunction Lead author: Gayle Nicholas Scott, PharmD, BCPS, ELS, Assistant Editor "The Natural Medicines Comprehensive Database identifies several concerns about the use of the components of Avlimil. Avlimil should not be used in pregnancy. Licorice, red raspberry, and black cohosh might have uterine stimulant effects which could induce premature labor. Women with hormone sensitive conditions such as endometriosis and breast, uterine, and ovarian cancer should also avoid the product. Several components such as red clover, kudzu, and black cohosh have estrogenic effects. Sage leaf, which is identified by product information as a "primary component" of Avlimil, contains the neurotoxin thujone. Sage is safe for occasional use in foods as a spice, but higher doses for prolonged periods might result in thujone toxicity. The thujone content of Avlimil is unknown". "Avlimil is dressed up to look like a prescription drug product, but it’s an herbal product that has not been approved by the FDA. Advertising cites an unpublished clinical trial of 40 women taking Avlimil for three months with good results, but there are no published trials. There is no reliable scientific evidence that Avlimil, or any of the herbs in it, has any effect on female sexual function. Avlimil costs more than a dollar a day. There’s nothing magical about Avlimil'’s eleven herbs…tell women not to waste their money".
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